Monday, October 15, 2012

Peanut company linked to salmonella outbreak expands recall

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Cabinet: Israel to head to polls January 22

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The Obsidian Door

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This forum is for OOC discussion about existing roleplays.

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hey everyone! i fixed a few thing in my roleplay The obsidian door, like adding a skelly into it. i hope somebody joins, it is a good RP.

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Elfangor19
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Sunday, October 14, 2012

Help Yourself Right now ? Self Help Tips And Techniques You Can ...

Boosting your daily life by way of personal development is an essential part to growing being an specific particular person. Environment and achieving objectives on your own helps to develop self esteem and self-confidence. This is very crucial just to be profitable in the things you do in your life. This short article will give you some ideas to help you obtain best personal development and growth in different places of your life.

A great suggestion for reaching greater personal development is to be practical instead of reactive when troubles come up within your daily life. Usually do not await something to travel wrong before you decide to do something regarding a difficulty, somewhat deal with all probable difficulties as finest since you can to achieve much more accomplishment.

Self improvement might be nerve-racking, since it features a lot of difficulties as you?re planning to modify old behavior. Attempt to lessen tension in your lifetime during this time. Minimizing anxiety can avoid overreacting to stressors. This makes each and every barrier very likely to be an ultimate good results, since overreacting makes us more vulnerable to missteps.

It?s by no means too soon to discover self improvement. Youngsters should be shared with and demonstrated they are capable of doing anything they established their imagination to. If this is ingrained within them from the time these are young, they are going to build a strong sensation of beneficial self worth that may stay with them in their daily life.

With personal development, be sure that you focus much more on what you will be presently efficient at and improve this to the highest potential. This is important since you can force forward and enhance yourself as an alternative to not creating any development and property of what contains you rear. Will not forget your weak spots, accomplish not permit them to pull you downward.

The world moves actually fast, and sometimes you could possibly think that you have not any other selection but to advance fast from it. This pushes one to make hasty judgements, or feel the need to anyway. It is essential to slow down making the proper choices since every determination you will make has an effect on your way of life.

If you would like turn into a better individual, usually do not hesitate to get genuine responses from other people. Occasionally, you are unable to watch your personal weaknesses simply because you do not have an objective look at oneself. Sincere feedback from others can be constructive and can help you establish places that you have to enhance.

Expect to get threats, think outside of the pack or put yourself outside the house your comfort and ease zone on the road to self improvement. This could be as silly as dressing in a Halloween night costume when you are 40 or as daily life altering as visiting a diverse land. Taking hazards allows us to be much stronger and experience difficulties head on.

As was stated at the beginning from the article, boosting your life by means of self improvement is an essential part to developing for an individual particular person. There are tons of several factors why men and women might want would like to improve their self improvement. Utilizing the assistance from this information will help you be moving toward attaining ideal personal development and growth in your life.

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Devil Survivor : The Four Gods

Devil Survivor : The Four Gods

Five years has already passed after Devil Survivor 2 arc. The four gods arise.

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Forum for completely Out of Character (OOC) discussion, based around whatever is happening In Character (IC). Discuss plans, storylines, and events; Recruit for your roleplaying game, or find a GM for your playergroup.
Welcome, welcome to my RP thread.

First, we need people who will be three other gods (or four); Seiryuu, Byakko, Genbu and Koryu... well, just submit your character here and we'll have fun together.

People talk about probability, I talk about something absolute like the fact that I am a demon, staying deep inside your heart, corrupting your mind and lusting for your blood. But I'll be there for you, in the pitch of darkness, or beneath the sunlight. That my vow to you

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harenezumi
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CDC reports new death in meningitis outbreak

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The Strangest Situation: A Culture of Compassion

This weekend?I have a little break in the Sanctum blog tour, and I want to shift back into my usual blogging habits to post on something a lot of folks are talking about, and with very good reason.

Bullying and harassment.

In this post, I'm speaking specifically about this phenomenon within our writing, reading, reviewing, publishing, blogging, book-celebrating community (because the topic in general is massively broad and can't be addressed in a single post!)

October is Bullying Prevention Awareness Month. It's a chance for all of us to sit down and ponder this phenomenon. It's not new, and no one's arguing that it is. However, the reach and impact of bullying and harassment?has clearly been intensified by technology, like so many other aspects of our lives. We're connected to each other 24/7, and we can speak to people who are thousands of miles away as easily as we speak to our neighbors, classmates, colleagues, and family. That brings a lot more people into our worlds, but in a very particular way: none of us have to look each other in the eye.

First, a definition. Bullying is not a synonym for criticism. It's just not. Bullying is an abusive, coercive behavior with the intention to intimidate or control its target. This is a repetitive behavior, not a one-time occurrence. Often there is a power imbalance. When this is happening online and between adults, it's called "cyberharassment" or "cyberstalking". In technical parlance, "cyberbullying" is a term reserved for when the?victim is a minor.

There have been many research studies on what makes for effective bullying prevention. You know what I've noticed? One factor seems to be a key determinant in stamping out bullying or harassment?within a system, be it a school, a workplace, or any other venue: CULTURE.

If the culture or climate of a place tolerates bullying/harassment or reinforces it, whether through active participation or silent complicity, cruelty will thrive.

In light of that, I have a few suggestions to help promote a culture of compassion while preserving our discourse. And I'm going to assume I'm talking to people who are not actively engaging in bullying or harassment. I also want to specify that I'm speaking not as someone who is above this fray, but as a member of this community. Everything I say below is something I'm working on doing, not something I've got down pat.

BE THE CHANGE YOU WANT TO SEE. Obviously, those aren't my words (they're Ghandi's). But I had to open with that because it's so powerful: We can't stamp out bullying if we don't carefully guard our hearts, mouths, and typing fingers from spewing hatred. And if we start to do this, we can step back from it--we can change our behavior. We can speak to each other with civility and respect while still disagreeing. It's not always easy, especially online where the emotional consequences of our actions are largely invisible to us. This means we also need to support each other to keep things cool. If we fire each other up in hatred, we're not helping--we're hurting. One truly awesome example of someone who uses her power for good is Maureen Johnson. I've become a huge fan of hers as I've watched her deal with people online with constant respect and measured civility, even when she vehemently disagrees with them. It's lovely to watch. It can't always be easy for her, but her online persona is an example of how to extend grace to others while being strong and assertive.

DON'T GO THERE. In the online world,?it's clear that?pageviews often reinforce bullying/harassing behavior (I've seen harassers say this themselves). The person who is?harassing sees how much traffic s/he's getting and takes it as a sign that people are enjoying watching the spectacle. Refusing to give someone an audience, as hard as it is (because outlandish, incendiary stuff is sometimes morbidly?entertaining to read, right? I admit my own guilt in this--I might read something and shake my head, but I'm still providing an audience, and I've been trying to stop that recently). Let's help each other resist providing a constant source of attention directly to the behavior we'd like to see go extinct.

SUFFOCATE THE FIRE.?Let's not speak directly to online bullies/harassers. Truly.? If you engage the harasser in a flame war, you're not helping.?That kind of intense connection often fuels bad behavior and sometimes costs well-intentioned people the moral high ground. We can't fight hate with hate.?If you feel yourself getting riled up and wanting to rage, STEP AWAY FROM THE KEYBOARD for at least several minutes. I'm not saying "stay silent." I'm just suggesting we direct our energy elsewhere, in a constructive way that will reduce harassment rather than intensifying it.

REACH OUT. If we witness someone being harassed and intimidated, let's reach out. THAT'S where we can put our energy. Especially to those who are vulnerable and not necessarily shiny, not popular, not established. Let's let?them know they are worthy of time and compassion. Let them know they matter. Let them know they are deserving of peace. We shouldn't be shy about telling others that we're happy to be sharing the world with them and that their voices can be heard. In fact, let's not wait until someone gets bullied to do this. Let's get in the habit of doing it now.

SPEAK OUT. If we do see bullying or harassing?behavior,?let's label?it and say that it's unacceptable. Alert authorities if applicable (website administrators, law enforcement under certain circumstances, advocacy groups). And if you are being bullied or harassed, do say so! A powerful example of this is Cassandra Clare's recent post about what she's gone through lately. She explains in detail what's happened to her--but makes it clear that talking directly to these?harassers is not the thing to do. She differentiates between criticism of her books (which is not bullying or harassment)?and what the people who are cyberharassing/cyberstalking her have done (whipping up outrage against her using false rumors and accusations, revealing personal details about how to find her, and a few other nasty things). She refuses to remain silent, but she channels all her energy into directing people to respond appropriately.

What say you? Shall we follow her example? Shall we openly and explicitly commit to a culture of compassion? Shall we support each other in civility and empathy (including forgiving the occasional slip up when it is accompanied by a commitment to re-engage in a kinder, more appropriate manner)? Shall we reach out to those who are vulnerable, and model treating every member of this community as worthy to share it with us?

So many of you can say this better than I can, and so many of you already do this more than I do. And so I will also say this: thank you for being good examples, and for being brave and speaking out. I am grateful.?You inspire me to be better.

Source: http://thestrangestsituation.blogspot.com/2012/10/a-culture-of-compassion.html

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Meningitis-linked firm sold drugs without requiring prescriptions: emails

BOSTON (Reuters) - The drug-mixing company at the heart of a deadly U.S. meningitis outbreak solicited bulk orders from physicians and failed to require proof of individual patient prescriptions as required under state regulations, emails to a customer show.

Reuters reviewed more than a dozen emails that show the New England Compounding Center, contrary to Massachusetts regulations, sold drugs without requiring physicians to supply individual patient prescriptions.

The customer confirmed that NECC supplied the clinic with drugs without patient names or prescriptions.

NECC, based in Framingham, Massachusetts, distributed thousands of vials of a contaminated steroid that has put 14,000 people at risk of contracting meningitis and killed 14 people.

The emails support assertions made this week by state pharmacy regulators that the compounding firm, which was authorized to deliver products only in response to patient-specific prescriptions, had violated its license in Massachusetts.

The emails also indicate that NECC referred business to a sister company, Ameridose LLC, despite a statement by Ameridose earlier this week that the two operated separately.

Both companies mix, dilute or repackage drugs that may not be easily available through a pharmaceutical manufacturer. They are owned by Gregory Conigliaro, an engineer, and his brother-in-law, Barry Cadden, a pharmacist who was in charge of pharmacy operations at NECC until it surrendered its license in the wake of the meningitis outbreak.

Ameridose has closed for 12 days pending state and federal inspections. Regulators say they have not found Ameridose's products to be compromised and they have not requested a recall. Ameridose maintains it is a separate entity from NECC with "distinct operational management."

"Although there is common ownership, the two companies operate under separate registrations and different licensure," Ameridose said on Wednesday through its public relations firm, O'Neill and Associates.

Another company, Alaunus Pharmaceutical LLC, which distributes drugs for Ameridose and is also owned by Conigliaro and Cadden, suspended its operations this week. Regulators said that among other things they would be looking at any "corporate governance" issues related to the outbreak.

In an email dated July 12, NECC regional sales manager David London Barron told NewSouth NeuroSpine, a neurosurgery and pain management clinic in Mississippi, that he had reached out to "our sister company, Ameridose" in connection with a request by the clinic for an anesthetic.

"Richard DeLibertis will be your contact - I have asked him to reach out to you as soon as possible to discuss your options," Barron wrote in the email.

On October 1, DeLibertis, identifying himself in an email as a regional sales manager for Ameridose, told NewSouth NeuroSpine that Ameridose did not currently have the anesthetic in stock but that it would add the clinic "to the list of those seeking the medication."

Barron did not respond to telephone or email requests for comment. DeLibertis did not respond to an emailed request for comment. O'Neill and Associates, which represents NECC and Ameridose, declined to comment on behalf of its clients.

PROMISE OF LOWER COSTS

Massachusetts prohibits pharmacies such as NECC, which create drugs that are unavailable from pharmaceutical companies, from selling medications without being in receipt of a prescription.?It is not illegal, however, for health care providers to buy in bulk from licensed pharmacies, of which NECC was one.

Emails between NewSouth NeuroSpine and NECC show NECC solicited bulk orders with the promise of lower costs in return for higher ordering volume - sometimes offering competitive price quotes for drugs that had not been ordered by the physician.

In July, Barron offered in an email to supply NewSouth NeuroSpine with 50 vials per month of a steroid at a cost of $20 per vial.

"If you are using approximately 50 per month your total yearly savings, if sourced through NECC, would be $4,500," Barron said in an email.

Frank York, the chief executive of NewSouth, told Reuters the center did not order or purchase the steroid from NECC. The products it ordered, he said, included items such as a contrast agent used in X-rays that the center could not get elsewhere in the dosages it needed and were provided without prescriptions.

And while the physicians were asked by NECC to fill out a "Prescription Order Form," the form acted more as a bulk ordering form than a standard physician's prescription, York said.

In one email, Barron asked the clinic to provide NECC with a list of patients scheduled for upcoming procedures "to correspond with the medication."

"If you are ordering 75 units we will need a representation of patients that you plan to use the medication on," Barron said in the email. "If one day's schedule has close to 75 patients that will be acceptable to fulfill the order. If it is easier for you to provide a simple list of names that would be OK too."

The clinic did not provide its schedule to NECC for patient privacy reasons, according to York, who added that the clinic did not receive any of the tainted steroid implicated in the meningitis outbreak.

Even without the names or individual prescriptions, however, NECC continued to supply NewSouth, York said.

Massachusetts health officials said at a press briefing on Thursday that NECC appears to have been operating in violation of the state's compounding pharmacy licensing requirements, though they did not go into detail.

"This organization chose to apparently violate the licensing requirements under which they were allowed to operate," Madeleine Biondolillo, director of the Bureau of Health Care and Safety at the Massachusetts Department of Public Health, said on a call with reporters on Thursday.

State and federal regulators in the briefing declined to say whether they previously knew about NECC's bulk sales to entities including the U.S. Department of Veterans Affairs. They said investigations were ongoing.

Regulators were not immediately available to comment on NECC's interactions with Ameridose.

While Massachusetts conducts periodic inspections of compounding pharmacies, the state does not track the volume of medications prepared and distributed at its licensed pharmacies, Biondolillo said.

(Additional reporting by Debra Sherman in Chicago, Svea Herbst and Tim McLaughlin in Boston; Editing by Ros Krasny, Mary Milliken and Lisa Shumaker)

Source: http://news.yahoo.com/meningitis-linked-firm-sold-drugs-without-requiring-prescriptions-175806039.html

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Saturday, October 13, 2012

JAKI'S BUZZ, LIVE RADIO ? OCTOBER 14TH GUESTS | Jaki's Buzz

Hello all you Buzzers!

Be sure and tune in this Sunday, October 14th to the JAKI?S BUZZ, LIVE RADIO show at 6pm at WESU FM 88.1, ( or stream online at www.wesufm.org).

This week we will be speaking with:

Kristin Huffman, Broadway: Tony award, Drama Desk, Outer Critics Circle and Drama League Awards for Best Revival of a Musical Company, playing ?Sarah? as well as flute, sax and piccolo. The production was filmed and aired on PBS?s Great Performances. Artistic director of The New Paradigm Theatre and she has a career that has spanned over 20 years professionally performing with operas, theatres, symphonies around the US/Europe. Former Miss Ohio/Runner-up Miss America. ( http://www.nptheatre.org/ and http://www.nptheatre.org/nptevents/broadwaystar-2/ )

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David Ryan Polgar,? entertainment attorney, educator, and award-winning columnist. He works with writers and filmmakers on copyright and contractual issues, and often presents on the topic and Fair Use and Copyright Law. Polgar will be speaking on entertainment law issues at the upcoming Hartford Flick Fest. ( http://www.davidryanpolgar.com/?) Listen this Sunday for a ?Listeners only? code?and be one of the 40 lucky listeners?to download your FREE COPY of?his latest work, Wisdom in the Age of Twitter,?being released through Libboo.com.

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Eileen Kaplan author of ?Laughter is the Breast Medicine? (?http://www.laughteristhebreastmedicine.com/?) ?is a thriver after having undergone a bilateral mastectomy in 2005 for bilateral breast cancer. Eileen focuses on a positive approach to life, using large doses of humor; advocating for women?s health; being a mentor to many and bringing the message throught her keynote speaking that you are the ?Queen? of you body, take advantage of all that is available in the medical world to keep yourself healthy.?

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Nat Lyon, singer/songwriter,?writes songs about the culture, environment, and history of New England.?Using dark humor, sarcasm, and a punk rock sensibility his music tells stories about real life in Connecticut.? He is not a typical folk singer- and his songs have been described as anthropological field notes set to music.?His CD, ?LCRV? (Lower?Connecticut River Valley)?is a collection of deeply personal songs dealing with universal themes, showing us something about ourselves in teh mirror of his own experience. ( http://natlyon.bandcamp.com/album/lcrv?)

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?LA ROUE ELAYNE at COBB?S MILL INN Presents a Staged Reading of Elizabeth Fuller?s

?ME AND JEZEBEL?

with Joel Vig and Elizabeth Fuller; Directed by Mark S. Graham

Sunday, Oct 14th, $15 Admission to the Reading

Reservations- 203-227-7221 (ext 26)

4pm doors open 4:45pm reading begins

7pm ?DINNER WITH THE STARS?

Prix fixe menu $25 (pd reservation required)

Cobb?s Mill Inn, 12 Old Mill Road, Weston, CT

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Source: http://jakisbuzz.com/blog/?p=1331

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Paramania Gliders: The Gtr Competition Reflex Paraglider And The ...

Besides the Yeti range from Gin, the RR Acro Wings paragliders, there are some other paraglider models that have managed to capture the imagination of amateur as well as professional pilots. This article will inform you about two such glider models, the Paramania GTR Competition Reflex Paraglider and the Paramania Revo 2 Reflex Wing. The section below has more information about these Paramania gliders in store for you.

The GTR Competition Reflex Paraglider: This unit according to the majority of the experts is the best competition paramotor wing currently existing on the market. You will have to be an advanced pilot for flying this particular Paramania creation. The name of the equipment has been derived from the initials of the Grand Tourismo Race.

There are few reflex paraglide models that are as well-equipped as this one. The strategically designed steering system and profile of the unit make it an easy-to use device. The device is also known for boasting advanced safety features.

The features that allow this competition paraglider to perform flawlessly include its huge wingtip area and lower aspect ratio. We have already mentioned that, this product can only be handled by an experienced pilot. However, that does not mean that the equipment is not easy to use and does not come with impressive safety features. This glider specializes in speed and precision; it possesses 100 percent reflex ability, which gives it the power of cutting through moderate turbulence. In spite of having such advanced features, this Paramania production is extremely user-friendly.

The Revo 2 Reflex Wing: This reflex glider from the house of Paramania is ENB rated. Unlike, the GTR, which is meant only for the advanced pilots, the Revo has been designed keeping the requirements of the newer and intermediate pilots in mind. However, advanced pilots will also find this equipment fascinating.

A perfectly planned makeover has made the Revo 2 a high performing gear. The company has created this model primarily for fulfilling the requirements of paragliding training centers and pilots looking for a perfect intermediate/beginner reflex wing.

Revo 2 has the EN B certification. Being a unit meant for the beginners, it allows easy launches and quick takeoffs. It is also prominent due to its enhanced directional stability or roll, which remains the same in flight and during launch. Landing the glider is also extremely easy due to its ability of flying at extremely low speed.

About the Author:
The person writing is article is a famous paraglider designer. He is also known for reviewing newly launched glider models. Products reviewed by him include RR Acro Wings paragliders, some Paramania gliders etc.

Source: http://www.articlesnatch.com/Article/Paramania-Gliders--The-Gtr-Competition-Reflex-Paraglider-And-The-Revo-2-Reflex-Wing/4209518

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France's Giscard d'Estaing hails Nobel award for EU

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Cells control energy metabolism via hedgehog signalling pathway

ScienceDaily (Oct. 12, 2012) ? Cancer, diabetes, and excess body weight have one thing in common: they alter cellular metabolism. Scientists from the Max Planck Institute of Immunobiology and Epigenetics in Freiburg and the Medical University of Vienna together with an international research team have jointly resolved a new molecular circuit controlling cellular metabolism. The previously unknown signalling pathway, acting downstream of the hedgehog protein enables muscle cells and brown fat cells to absorb sugars without relying on insulin. Substances that selectively activate the signalling pathway could thus be utilized in the treatment of diabetes and obesity. With their results, the researchers are also able to explain why various new anti-cancer agents have induced mysterious pronounced side effects in the clinics.

Hedgehog was initially identified as an important protein for embryonic development across various organisms. Without hedgehog, the physiological partitions of the embryo become indistinct. However, hedgehog also influences replication, migration and specialisation of cells ? that is, the processes that also play a role in carcinogenesis. Mutation of genes also occurs concomitantly in various types of cancer, such as pancreatic, gastric or intestinal carcinomas. Above and beyond this, hedgehog inhibits the formation of ?bad? white adipose tissue. Brown or ?good? fat that serves to control body temperature, however, remains unaffected.

Hedgehog is therefore a very promising target for medications that fight cancer, diabetes and excess body weight. The US Food and Drug Administration (FDA) approved the first hedgehog inhibitor, Vismodegib, for treatment of cancer this year. There are presently at least six further agents being tested in clinical studies. Surprisingly, the first patient cohorts receiving Vismodegib have shown serious side effects, such as weight loss and muscle cramps, to the extent that more than half of the participants in the studies had to discontinue use.

The new research results appear to explain the mysterious cramps and suggest an easy, safe and already available adjunct therapy to resolve the complication. The researchers discovered a new hedgehog signalling pathway that is independent of the activation of transcription factors and genes known thus far. Cells control their primary energy metabolism, including the glucose, fatty acid and amino acid metabolisms, via this pathway.

The membrane protein known as Smo plays an important role here. Smo controls the known signalling pathway through transcription factors, as well as the new pathway via a much faster AMP-kinase enzyme and calcium dependent pathway. Smo is activated if hedgehog binds to a specialised receptor in the cell membrane. In the signalling pathway that has now been discovered, calcium flows through the membrane channels into the cell and activates calcium-dependent enzymes that in turn activate the AMP-kinase. This completely rewires metabolism. The cell can rapidly absorb large quantities of glucose using the AMP-kinase and other enzymes, rebalancing anabolism and catabolism. Further, rather promoting efficient energy metabolism through mitochondria, the new hedgehog signalling pathway prompts much less efficient via lactic acid fermentation ? a process with which cancer cells use to acquire their energy without oxygen, for example (Warburg effect).

Even more surprising, the new pathway is stimulated promiscuously by both classical activators and inhibitors of the old, ?canonical? hedgehog pathway. This finding potentially flips the interpretation of tens, if not hundreds of research papers in the field. Still not clear, this could be one additional reason why hedgehog inhibitors are so effective, in essence they starve the cancer cells from the inside.

Counterintuitive inhibitor-based activation of the hedgehog and Smo-calcium/AMP-kinase signalling pathways interferes with anabolic metabolism. ?Activation of the AMP-kinase and increased catabolism could explain the exaggerated weight loss of the participants in the clinical studies. More importantly though, the influx of calcium into muscle cells leads to instant contraction, and must be triggering the cramps,? explains Andrew Pospisilik from the Max Planck Institute in Freiburg. Importantly, Hedgehog inhibitors do not have to lead to these side effects. ?We targeted the Smo protein with various substances and found out that there are inhibitors that do not evoke an increase in calcium or glucose values, and critically, these same inhibitors fail to cause muscle cells to contract in culture. The development of medications such as these, which have minimal side effects, is therefore entirely possible," says Pospisilik.

In addition, again using fat cells, the scientists find that cells dramatically increase the glucose quantity they can absorb ? without relying on insulin. Glucose-tolerance tests on mice confirmed the findings. This was accomplished by administering a specific amount of glucose via the food and measuring the blood glucose concentration afterwards. Mice that had previously been treated with the classic hedgehog inhibitor cyclopamine had correspondingly lower blood glucose than untreated animals. Apparently, cyclopamine increases the glucose absorption, but only in the brown adipose tissue and various types of muscle tissue. Thus, researchers measured an increase in body temperature of around one degree ? a sign of higher activity in brown adipose tissue.

?Agents that only activate the Smo-calcium/AMP-kinase hedgehog signalling pathway are therefore candidates as medications for treating excess body weight, as well as type-1 and type-2 diabetes. Similar to the broad hedgehog inhibitors, they possess the potential to induce muscle cramps. Thanks to our findings, we now know that a new agent must first be tested on muscle cells before it is used on humans,? says Harald Esterbauer from the Medical University of Vienna.

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Story Source:

The above story is reprinted from materials provided by Max-Planck-Gesellschaft.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Raffaele Teperino, Sabine Amann, Martina Bayer, Sean?L. McGee, Andrea Loipetzberger, Timothy Connor, Carsten Jaeger, Bernd Kammerer, Lilli Winter, Gerhard Wiche, Kevin Dalgaard, Madhan Selvaraj, Michael Gaster, Robert?S. Lee-Young, Mark?A. Febbraio, Claude Knauf, Patrice?D. Cani, Fritz Aberger, Josef?M. Penninger, J.?Andrew Pospisilik, Harald Esterbauer. Hedgehog Partial Agonism Drives Warburg-like Metabolism in Muscle and Brown Fat. Cell, 2012; 151 (2): 414 DOI: 10.1016/j.cell.2012.09.021

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/eIXIjrK5kvE/121012112159.htm

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Friday, October 12, 2012

Romney and Obama as average Joes: many differences, yet a ...

Politics are a never ending battle between who?s right and who thinks they are right, though all poking and prodding aside, Mitt Romney, or actually Willard as his first name actually is ? seems to be a decent guy. Back in the day and up to this point in time, he has been a family man. He and his wife Ann raised 5 boys Tagg, Matt, Josh, Ben and Craig without any extra help as Mrs. Romney claims, and all have become successful in their endeavors. Most have chosen the same path as their father, being a father themselves, all of them married. Ben is the only Romney who?s childless, yet has a yorkie-poodle mix which Mitt calls his grand-dog. The Romney?s are very family oriented and have bundles of grandchildren, 18 to be exact.

?In this life, the commitments that come closest to forever are those of family,? Mitt Romney said coherently as he addressed the Liberty University Class of 2012.

Family values like having dinner with his kids and grandchildren are definitely approved of, by voters. Being able to stick to rules and keep your word are grand qualities any president in the running should have, and Mitt Romney has proven that through his religion?s strict guidelines of no booze, no coffee, and no smoking.

Perhaps the reasons listed above could be why some Americans gawk over his stature, his pristine values and charismatic speeches. In fact, millennials better known as the youth vote is where one survey discovered intriguing findings. If a millennial was taken to a voting booth in their childhood, they were significantly more likely to vote when they became of age, according to the Public Religion Research Institute. This sort of parental example coincides with the fact that family does hold its weight in elections as a whole.

Shifting over to the baby boomers, where some of them are now entering into retirement age, a second survey points out their attitudes on life including family values. The Pew Research Center found baby boomers to be less accepting of same sex couples raising children and couples cohabiting without tying the knot. Keep in mind, as Mitt has stated before, he is against gay marriage, not to mention abortion.

Yet it is certain to note that he is not the only candidate playing the family card here, Barack Obama is doing so too. Why, back in 2008 when he was elected into office, he promised his 2 daughters, Sasha and Malia that they would get a puppy if they moved into the White House. He kept that pact with them and now the Portuguese water dog, Bo is already 4. But, his values look slightly different from Romney?s.

As Romney conceals his first name from the public eye, Obama does the same with his middle name Hussein?which is not even in the top 1000 male names for the last 12 years, according to the Social Security Administration in the US, neither is Willard though.

?When we?re in town here in Washington, in the evenings, six thirty we want to be at the dinner table with the kids and I want to be helping with their homework,? said Barack Obama in an interview with CNN?s Jessica Yellin.

Although Obama?s family get-togethers seem transparent, we hardly ever see Obama with his aunt or uncle. Uncle Onyango has been accused of evading a deportation order and Aunt Zeituni had donated money to his previous campaign, a prohibited act since she is an illegal immigrant.

We see his extended family, but sadly in a dim light in the news. Even Sasha and Malia are pushed away from the bright lights and media spots but for good reasons. Mrs. Obama wants them to have a normal childhood. When faith comes into account, the Obama clan is said to rarely attend church on Sunday, a very family oriented activity and he is still perceived by some Americans as a Muslim. Romney on the other hand is said to go to church almost every Sunday, a stark contrast from how the Obama family deals with religious gatherings.

Harvard made and politically driven, these inquisitive men have much to offer the public. They have tax proposals, an initiative to jump-start jobs, and an excitable talent of muddling their opponent?s words. Take away the political fights though, and we can see 2 dedicated families who have core values that encompass love, compassion, and protection over their offspring. Their religious practices and honorary awards may differ, but in the end they are just like the rest of us. All they crave is acceptance ? not just by voters, but especially by their one and only family.

Source: http://english.ruvr.ru/2012_10_11/Romney-and-Obama-as-average-Joes-many-differences-yet-a-powerful-similarity/

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Michelle Obama: Malia and Sasha Focused on Homecoming, Not Election!

If in four weeks your dad were running for re-election and you would learn if you would remain in Washington another four years or move on to a new chapter in your young life, you would think you might feel slightly stressed. Listening to Michelle Obama talk about Malia and Sasha, you get the sense they aren’t feeling anxious at all, which is fabulous to hear.

Source: http://www.ivillage.com/michelle-obama-malia-and-sasha-not-focused-election/1-a-493318?dst=iv%3AiVillage%3Amichelle-obama-malia-and-sasha-not-focused-election-493318

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C ? Community | My Whole Foods Kitchen. com

GATHER? WITH? OTHERS

I was teaching classes and trying to write this cookbook while also keeping up with all of the self-reliance cooking I was committed to.? It was more than one person could do.? My husband took up the slack by taking on certain food production projects each week.? He loves to make mayonnaise, hummus and tomato sauce.? He doesn?t mind whipping up breakfast or dinner as long as I have all the necessary ingredients ready, such as homemade yogurt, pitas, pizza crust, butter, soy milk and dry mixes for waffles, pancakes, crepes, and Mega-Meat.

After a strenuous year of trying to do both teach and keep up with my own home-making goals I found that I wasn?t able to do both. I had to choose one or the other.? I had to choose my home and family, of course.? That is the whole point of writing the book!? I know that if I stop being a producer so that I can go to work to be a successful teacher and business woman promoting my book, I will not be living out the lifestyle I am preaching! ?So I switched my focus from teaching to filming home videos of My Production Schedule.? Visit youtube.com/3DHealth.? This turns out to be a better way to demonstrate and teach anyway.? I don?t have to advertise.? I don?t have to drag all my pots and pans.? And I don?t have to supply samples!

Though I learned how to make all of the groceries on my shopping list and eliminated trips to the store, I found that it took great organizational skills to keep track of it all.? The makings for each meal had to come together at one moment in time.? When I make bread dough I usually don?t have the energy to also make my own pizza sauce and mozzarella cheese for pizza on the same day.? I had to pace myself and just do what I can with the amount of time and energy I had.? So I made a Production Schedule that divided all the tasks into projects and assigned them to specific days each week so that all the groceries would be ready in time for the meal they were intended for.

My Production Schedule begins Sunday with the soaking of the beans for the week. ?Then Monday I cook them up.? I serve my rotating meals that circle around beans, grains, nuts and seeds for protein instead of meat.? If I didn?t get the makings done in time for the meal coming up, we simply waited until the last minute and ran to the grocery store to get that one thing.? This is a very low-pressure way to learn rather than waiting until we are in the middle of a food shortage to begin thinking about finding a cookbook and learning how to make our own food. ?Even if you already have the food stored, it still takes much effort to learn how to cook with them.? It is not feasible that this learning curve could take place during a crisis.? It is only logical to learn before the crisis comes.

Our lifestyle is getting easier, while our body, mind and spirit suffer. Our life, the only life we have been given, is ?carelessly used up? with the task of earning a paycheck to buy the necessities of life, instead of creating the necessities of life with our own hands. The activities that once exercised the body and fulfilled the soul such as digging in the soil, carving wood or kneading bread have all been eliminated and replaced with activities that bring stress and emptiness such as telemarketing or bill collecting.

I made a commitment to myself that I would one day stop shopping at the local grocery store.? I am committed to produce everything I am able; beans, cereal, snacks, cheese, butter and bread.? I can grow my own vegetables and fruits.? I can create foods to replace meat and dairy products. ?As I became more proficient at producing my own food and more committed to producing rather than consuming, I found that the big jobs could be broken down into smaller, more do-able chores and dispersed over the days of the week. Each time I did any baking or cooking, I multiplied my efforts by making enough for the whole week rather than just enough for one meal for one day.

Using My Rotating Menu, I knew exactly what I was going to make each week.? Now, with My Production Schedule, in the Part 3 of this book, I filled my refrigerator and freezer with meals I made ahead. With a lot of planning and experimentation I was able to gather and store the foods I was using regularly, to eliminate time spent shopping each week. I was able to come up with dry mixes for anything that I made often, to eliminate the preparation time for each meal. I was able to make bread for the week knowing exactly what kind of bread I was going to need for each meal that week; pitas, pizza crust, subs, rolls, etc. ?I was able to plant a garden and produce fresh vegetables and fruits and even freeze and dehydrate some ahead for later in the season when the garden would be resting.? I was able to make replacements for meat and dairy products for the week with plant sources by learning to make soy milk, almond milk and mega-meat. ?Each step I learned to do, gave me that much more variety to offer my family and improved my family?s health significantly.

As my life became more and more complicated with the expos I was attending and conferences I was offering and books I was writing, my husband took up the slack, taking the responsibility for all of the regular production schedule that I had been doing. The kids pitched in too. Then my husband landed a job out of state and had to be away.? All of my food production came to a screeching halt.? My garden needed watering.? My beans weren?t getting cooked.? My mail was stacking up and my emails were out of control.? I had deadlines to meet and no one to help.

This situation made it so real to me that if we were ever going to be able to keep this up, we need a community to work with.? We can?t do it all. If we are going to go back in time, so to speak, to make our own bread and our own cheese, milk our own cows or raise our own chickens, we must also go back in time to an interdependent lifestyle where everyone worked together.? We must have support and assistance.? If the cow needs to be milked and I have to be teaching a conference in another state, I must have neighbors and friends who are equally invested in the cow who will milk the cow!

This is when my mind went to work designing and planning a community that would work together and pool all the skills, energy and resources they have for the good of all.? It?s not a new idea.? It?s an old idea that has been lost because we don?t need each other anymore.? We can go in and out of our homes and never say hello to our next door neighbor.? Everything we need it at the superstores.? We can go in and out of a superstore and never run into anyone we know.? With automated check-out stands we do the whole thing without speaking to another soul.

I wrote a plan that I hope will start the conversations going about creating a more interdependent lifestyle.? I know I need people in my life, and I can?t be the only one that does.? As I talk to people about the ideas I have been kicking around, every one of them have said they thought about the same thing.? It is on the hearts and minds of the thinkers of our society.? We know that some parts of our society are changing drastically.? Our cities, as they are designed today, may not be the best place to be if and when food shortages begin and civil unrest arises.

In the midst of this revelation about community that was coming to me, the city was doing some repairs on a water main in our neighborhood and our water had to be turned off the whole day.? The whole street had its water turned off.?? I couldn?t run next door, establish a friendship with a stranger, to use his bathroom or to wash my face or brush my teeth, because his water was off too.? It suddenly occurred to me that a crisis could come at any moment that cut the water off for a period of time and if everyone in the neighborhood has their water off at the same time, we would all be in a lot of trouble.? Water is the one thing that you cannot do without?even for a short time.? I bought four 50-gallon barrels several years before this when I first started learning about self-reliance.? They are full of water and ready to use in my garage.? I was the only one on my block that had water for this minor reality check.

I began to gather with other families to experiment with an interdependent lifestyle.? My garden buddies and I worked together to make meals straight out of the garden.? My friend made zucchini relish enough for both of us.? I made salsa and tomato sauce for both families. This greatly increased what we could do with our own time and productivity.? This is when life starts to get interesting.? This is the secret to world hunger.? Not mass producing for the entire planet so that they don?t have to do anything but shop, but instead increasing individual self-reliance and interdependent production to assist each other to have more time and energy for greater things than just eating!

There is nothing more therapeutic than digging in the soil, breathing in fresh air, getting sun on your face and eating fresh produce from your own garden. This is the exercise that improves health in body, mind and spirit.? This is the well-being that you can?t bottle and sell as a medical cure even though it is more effective.? Combine this with the sense of community that fills the soul when many people work together, nothing else can compare.? This is what we were intended to do with our time, our energy and our strength.

I worked together with my neighbors in a community garden.? We found an elderly gardener who could no longer continue to keep up with her beautiful garden and yard.? She was an extraordinary gardener with all the tools we could ever want. She had planted and nurtured grapes, figs, apricots, mulberries, pomegranates and a large, well fertilized garden spot.? When she went to live with her daughter, a few families helped her by taking care of her yard and keeping it watered.? She in return allowed us to garden in her garden spot and reap the fruits of her years of labor that went into preparing and establishing that little piece of ground.? It was a win/win partnership.

By working as a group we added even more therapy to the garden experience by learning to work together, sharing and being generous with the riches that come from the sweat of our brow. I loved it!? Look around your neighborhood.? There may be a situation close by where you can garden with a community of like-minded people or bring new life and vitality to an elderly neighbor?s yard.? Or if you have plenty of garden space, why not invite neighbors and friends to work with you to create something far more spectacular than you would be able to do by yourself.? There are those around you who have no land to work with and would love an opportunity to learn how to garden.

We found another spot of ground that was up to our waist in weeds and seemed to be abandoned.? My friend, Deborah Curtis, said this little spot of ground ?called to her? every time she walked her children to school. With a little detective work she was able to contact the owner of the abandoned property and get permission to garden there.? They had access to irrigation water that came every five days for a yearly fee.

We paid the fee, cleaned up the yard and dug ditches to distribute the water as it came into the yard. Many families worked together to dig the long ditch that took the water from one end of the yard to the other. A community filmmaker stopped by to film what we were doing and ended up putting his camera down and grabbing a shovel.? There is something contagious about gardening!

I wanted to have enough tomatoes to bottle salsa for the year.? For our family that would be 24 pints.? In order to have so many ripe tomatoes at one moment in time you have to plant 20 tomato plants or more?way more than one family would need.? If there are more families involved, they can plant 20 tomato plants together and then harvest them in turns to make all the salsa or tomato sauce they want at one time.

I made a goal for my family to eat out of the garden entirely as long as it was producing a bountiful harvest.? I allowed myself absolutely no trips to the store to buy produce.? We ate gourmet meals every day of the week.? I abandoned all my food production such as making bread and cooking beans.? We didn?t need so much food.? We were able to create meals from the garden without much else added; chili rellenos, colorful salads, stir fry, spaghetti squash, or pizza topped with tomato sauce made from garden tomatoes, garlic, onions, basil and oregano. It was food heaven.

I planted new seeds as soon as my plants were done producing.? This keeps the garden at its maximum production at all times.? Next, I made a goal for myself to keep things growing in the garden during the winter months.? Potatoes, carrots, beets, turnips, onions, garlic, spinach and bok choy are able to live and survive mild winters.? I also found out that Winter Wheat is planted in the fall and harvested in the Spring.? I have so much Winter Wheat in my food storage, I felt like I had to try planting some.? After all, if one grain of wheat produces 20 grains, then one bucket produces 20 buckets. Where will you find better increase from any other investment?? If I could plant the whole foods I had stored, I could replenish my stores without spending any money in the years to come.? That sounded very intelligent to me.? I wanted to try it.

My trips to the store were diminishing significantly.? We were down to a few grocery items that we were not able to produce; eggs, milk, ice cream, butter, cheese, honey and chips!? I realized that in the Old Testament God promised a land ?flowing with milk and honey.?? That means a land that had cows and bees. I began to wonder, though I lived in a city and didn?t own land, how I could reap the benefits of a ?land flowing with milk and honey.?? I decided that our garden area would have to expand to produce some of these products.? I fenced off a small area in a shady corner of the yard where we gardened and got three chickens about half grown. In a few months we have more eggs than we could keep up with. Next, I have my eyes on a bee hive set up as soon as we got the money. ?I want that ? cup of honey for my bread each week and 1? c honey for my granola once a month or so.

Finally, I talked around to people in my community to see if anyone else wanted to own a milk cow with me. People thought I was crazy.? I looked into boarding a cow at the nearest horse boarding stables. My plan was to split up the boarding costs, the feeding costs and the milking chores.? A cow has to be milked and fed twice a day.? That is 14 cow chores a week.? If 14 people owned the cow with me, we could decide which milking we wanted each week and be satisfied with the amount of milk that came from that one milking.? If there was a larger family, they might want to buy two shares of the cow and milk twice a week.

I chose to set my sights on a cow instead of an easier animal such as a goat or sheep because I wanted the cream more than I wanted milk.? I believe dairy products?especially cream, have gotten a bum rap in the last few decades. If God blesses us by giving us a land flowing with milk and honey, then milk can?t be detrimental to my health in moderation. As with anything, it is the over-indulgence that causes health problems, along with the lack of exercise and the lack of fresh produce in our diet.

I felt sure that I would find a way to have a warm, giving milk cow and I know it will add so much to our lives.? Not only will she supply milk and cream, but she will bring us self-reliance to a much greater degree.? One of the students that came to my cooking class, Harmony, knew someone who had a milk cow about 20 minutes out of town.? She arranged for us to go out to meet the cow and see if we wanted to buy her. We decided to visit her and milk her once or twice a week and get a feel for how much milk or how many ?milkings? we would actually need for our families.? We planned to make all of our own dairy products and no longer purchase these items at the store.? This would eliminate from our diet the denatured dairy products full of harmful antibiotics and hormones that we find at the store.? We love the cream that rises to the top and the smooth sweet flavor of unpasteurized, un-homogenized, fresh, whole cow?s milk.? We learned that some people who were allergic to store-bought milk could drink fresh milk without symptoms.

As my vision for the community cow expanded, I started to see why our country is not doing well on so many levels.? The economy is slowly declining because we are not doing what we always did before.? We are not owning land and providing for our basic needs from the land.? Instead we are paying rent or mortgage payments that require cash currency.? You can?t pay your rent with the extra tomatoes from your garden anymore.

This is when I saw for the first time that we need to reform our economy to take a few steps back in time.? As we began to create automation and transportation we won the race but went sailing past the finish line and didn?t stop. The finish line must be where maximum human health and happiness lies and where there is abundance for all.? If we automate ourselves out of having a garden, we lose more than we gain: sunlight, soil, fresh foods, camaraderie, self-reliance and satisfaction.

This is true in so many aspects of modern life. When we have transportation, we no longer walk long distances and then suffer the health consequences of inactivity.? When life is so easy, we no longer need each other to survive and therefore lose the relationships that are built on interdependence. If we are separated from everyone else and no longer believe it is any of our business if people on the other side of town go hungry or in some distant land people are suffering from starvation, what did all of our automation and advancement gain for us?

Interdependence is my plan for a community that is self-sustaining, off-the-grid, humanitarian with the one and only goal of ABUNDANCE FOR ALL.? When you set your sites on abundance for all and not just abundance for your own household your decisions and choices change drastically.? I loved writing this book as much as people seem to love reading it, because it is my proposal to an intelligent society to create a better life for ALL, not just for ourselves.? In so doing, life becomes better for ourselves as well.? Do you prefer living on a planet where everyone is doing well or where some are starving and some are obese?? All of us would be much happier living in a world where there is abundance for all.? (See 3DCommunity.Us to order the book Interdependence).

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Community Gardening

My first year of community gardening, since I was just learning, I took one section of the garden and my neighbors took the other sections. My second year, however, in a new situation with new garden buddies, I persuaded them to garden as a community rather than in separate individual sections.? This gave us more space to work with to be able to plant a greater variety of plants and eliminated the duplicates of the same plant.? If everyone is assigned their own area, they each have to plant their own zucchini when one bush of zucchini is more than enough to feed several families. They each have to plant a cherry tomato when one bush is enough to feed several families. ?This makes sense to me.? Why work separately and repeat the same effort over and over again when you can work together and divide the harvest?

Another reason I wanted to join the garden into one instead of separate sections is because they told me a story about one of the families who dropped out mid-season for personal reasons last year and didn?t weed their area. It became an eyesore and didn?t produce because it didn?t get necessary water or attention. This family didn?t say why they weren?t coming, but made excuses and apologies. Because they had established separate areas, no one felt they had the right to step in and take that part of the garden.? It was awkward and resulted in a lack of productivity of that part of the garden.? When this same family wanted to be involved again the next garden season the others warned me that this family would not do the work, though they seem to have an interest in being part of the group.

To me the answer was simple, and luckily they all agreed.? If we all plan the garden together and combine finances to pay for the seeds, plants and supplies, and work together to put it all in the ground then about the time some families lost interest is when the biggest part of the work has been accomplished.? I saw that as a plus rather than a minus.? If the family drops out again mid-season then there will be more for us!? It turned out to be just that way and there was plenty to share with the family who lost interest come harvest time.

I believe we have to get out of the mentality that there is not enough to go around.? The garden vividly demonstrates that there is so much to go around.? The harvest is always enough to create abundance for all.? We ended up giving beautiful, colorful, fresh fruits and vegetables to neighbors and friends that didn?t help at all.? So what difference does it make how much time one puts in more than another?? Everyone benefits no matter how it all plays out.? It?s true that many families will ?dig in? and help at the beginning and then lose interest.? I always put more hours into weeding and maintaining the garden than anyone else, but that is because I wanted to.? I loved every minute.? I was grateful for the garden spot because where I lived didn?t have a garden spot.? I was grateful for any help I got.? What is the alternative?? Get fed up with people for not helping and go garden by myself?? What did I gain?? I have to do the whole thing myself and will still end up giving much of it away to people who didn?t take part in any of the work.? But now I have to pay for all the supplies, prepare the spot myself, do all the planting, watering, weeding and reap an abundant harvest and give much of it away. Yet so many people feel better about this plan than giving their harvest to people who didn?t help ?enough?. It is all about letting go of expectations and letting people do what they want. And feeling free to spend the time you want in the garden without feeling obligated to do more than you are able.? If you can?t keep up with it all, then there will be more weeds than you want.? It?s not life or death.? Maybe it will motivate one of the other families to ?dig in? and help.

The following year my own life and priorities changed while I was writing the book, Interdependence, and I was the slacker that didn?t come to the garden much.? But I didn?t feel a bit guilty because I had helped to pay for the water and supplies. I tried to get there more often, but I was immersed in creativity and loving it. My focus had to shift that year in order to progress in my own life.?? Life is always changing.? The trick is to cooperate and support people during their shifts and let them support you during yours.? If enough people are working together it won?t have such a huge impact if one person is not focused for a period of time.

Source: http://mywholefoodskitchen.com/?p=1460

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